The most recent medication that has been approved for weight management by the TGA is a combined GLP1-GIP agonist. This medication has been approved in Australia for over a year for the treatment of Type 2 Diabetes.
With regards to reducing the risk of developing Type 2 Diabetes in patients who have overweight or obesity, this new medication has been shown to reduce this risk by 94%!
GIP/GLP-1 receptor agonists work by activating two incretin hormone receptors. GLP-1 is a regulator of appetite and caloric intake. Nonclinical studies suggest the addition of GIP may further contribute to the regulation of food intake.